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RESEARCH

The MuSK-BMP Pathway

Much of work in our laboratory is focused on the MuSK-BMP pathway. Originally discovered by Atilgan Yilmaz, a former graduate student in the lab, we found that MuSK is a BMP co-receptor shapes transcriptional output to BMP stimulation (Yilmaz et. al., 2016). Importantly, MuSK is only expressed in restricted set of cell types and thus it offers a precise avenue for manipulating BMP signaling in specific contexts (Fish & Fallon, 2020). We are pursuing this in vivo role in several contexts.

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Adult Hippocampal Neurogenesis and Plasticity

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Muscle stem cells (satellite cells)

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